Title:
インダニルオキシジヒドロベンゾフラニル酢酸
Document Type and Number:
Japanese Patent JP5853317
Kind Code:
B2
Abstract:
The present invention relates to compounds defined by formula (I) wherein the variables R1, R2, R3, m, and n are defined as in claim 1, possessing valuable pharmacological activity. Particularly, the compounds are activators of the receptor GPR40 and thus are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.
Inventors:
Himmelsbach Frank
Backer remco
Eckhart Mathias
Humprecht Dieter
Lang Cop Elke
Wagner Holger
Backer remco
Eckhart Mathias
Humprecht Dieter
Lang Cop Elke
Wagner Holger
Application Number:
JP2013541333A
Publication Date:
February 09, 2016
Filing Date:
November 30, 2011
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D307/80; A61K31/343; A61K31/351; A61K31/352; A61K31/4155; A61K31/4178; A61K31/42; A61K31/443; A61K31/4725; A61K31/497; A61K31/506; A61K31/5377; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P9/00; A61P9/10; A61P43/00; C07D405/12; C07D407/12; C07D413/12
Domestic Patent References:
| JP2005343792A | ||||
| JP2005015461A | ||||
| JP2012529422A | ||||
| JP2010508268A |
Foreign References:
| WO2010045258A1 | ||||
| WO2009157418A1 | ||||
| WO2007114213A1 | ||||
| WO2007033002A1 |
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Akizawa
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Akizawa