Title:
改善された免疫反応を誘導するワクチン
Document Type and Number:
Japanese Patent JP5894604
Kind Code:
B2
Abstract:
The present invention relates to a pharmaceutical vaccine composition comprising: (a) a pathogen-derived antigen selected from the group consisting of Mycobacterium tuberculosis antigen, Bacillus anthracis antigen, HAV (hepatitis A virus) antigen, HBV (hepatitis B virus) antigen, HCV (hepatitis C virus) antigen, HIV (human mmunodeficiency virus) antigen, influenza virus antigen, HSV (herpes simplex virus) antigen, Hib (Haemophilus influenzae type b) antigen, Neisseria meningitidis antigen, Corynebacterium diphtheriae antigen, Bordetella pertussis antigen, Clostridium tetani antigen and Varicella virus antigen; (b) a deacylated non-toxic LOS (lipooligosaccharide); and (c) a pharmaceutically acceptable carrier.
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Inventors:
Cho Yang Jae
Lee Na Kyung
Jang Jin Wook
Kim Kwang Sung
Yoo Won-il
Lee Na Kyung
Jang Jin Wook
Kim Kwang Sung
Yoo Won-il
Application Number:
JP2013544403A
Publication Date:
March 30, 2016
Filing Date:
December 17, 2011
Export Citation:
Assignee:
Igen Inc.
International Classes:
A61K39/25; A61K39/39; A61P31/22; A61P37/04
Domestic Patent References:
| JP2007537248A |
Foreign References:
| WO2010023260A1 | ||||
| WO2006121232A1 | ||||
| WO2009082664A1 |
Other References:
J. E. Han et al.,International Immunopharmacology,2010年 2月,vol.10, No.2,p.169-176
H. U-Hansson et al.,Cellular Microbiology,2004年,vol.6, No.7,p.625-637
G. Fedele et al.,Microbes and Infection,2007年,vol.9,p.855-863
H. U-Hansson et al.,Cellular Microbiology,2004年,vol.6, No.7,p.625-637
G. Fedele et al.,Microbes and Infection,2007年,vol.9,p.855-863
Attorney, Agent or Firm:
Koichi Hirota
Yoshihiro Nagare
Naoko Matsuda
Yoshihiro Nagare
Naoko Matsuda