Japanese Patent JPH0523260

B2

A pharmaceutical composition effective in the protection of normal tissues against radiation induced damage comprising administration a compound of the formula R1-CO-NR3-/A/-S-R2 in which R1 is a radical corresponding to an amino acid R1-COOH, /A/ is a C2 or C3 alkylene radical which can be substituted with a C1 to C3 alkyl radical, or with a hydroxy or hydroxycarbonyl radical or a -COR radical where R is an amino or -NH-CH2-CO2H radical, R2 is an acyl radical which protects the thiol group and which liberates the thiol group in vivo, R3 is a hydrogen, and also the salts of this compound with pharmaceutically acceptable acids.

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OIRI JOERU
ANBATSUSHU JAN RUI

JP50244384A

April 02, 1993

June 21, 1984

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SANTORU NASHIONARU DO RA RUSHERUSHU SHIANTEIFUITSUKU

A61K31/155; A61K31/16; A61K31/255; A61K31/265; A61K31/395; A61K31/66; A61K38/00; A61P35/00; A61P43/00; C07C67/00; C07C313/00; C07C323/59; C07C325/00; C07C327/20; C07C327/38; C07C329/00; C07C333/02; C07C333/14; C07C335/30; C07C335/32; C07C381/02; C07D283/00; C07F9/165; C07F9/22; C07K5/00; C07K5/06

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