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Document Type and Number:
Japanese Patent JPH0546348
Kind Code:
B2
Abstract:
The invention relates to new oxidiazole-alkyl-purine-derivatives of the Formula I and pharmaceutically acceptable salts thereof wherein A stands for C1-4 alkylene and R1 represents C1-6 alkyl, hydroxyalkyl, halogenoalkyl, carboxyalkyl, C5-6 cycloalkyl or aminoalkyl of the Formula -(CH2)n-NR2R3 in which group n is an integer 1-3; R2 and R3 each stand for hydrogen or C1-4 alkyl or together with the adjacent nitrogen atom they are attached to form a 5- or 6-membered nitrogen containing heterocyclic ring which may optionally comprise a further nitrogen atom or an oxygen atom as heteroatom; or R1 stands for phenyl, hydroxyphenyl, carboxyphenyl, benzyl or dimethoxybenzyl The compounds of the Formula I can be prepared by methods known per se and can be used in therapy as antitussive agents.

Inventors:
DEJEE KORUBONICHI
EMIRU MINKERU
ZORUTAAN BARUGAI
GERUGEI HEEYA
GAABORU KOBAACHI
AAGUNESHU GOTSUCHEGEN
SHAANDORU ANTOSHU
SHAANDORU BIRAAGU
ANDOREA BOREROBUSUKII
IENEE MARUTON
KATARIN MAARUMAROSHI NEE K
Application Number:
JP25451387A
Publication Date:
July 13, 1993
Filing Date:
October 08, 1987
Export Citation:
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Assignee:
CHINOIN GYOGYSZER ES VEGYESZET
International Classes:
A61K31/52; A61K31/522; C07D473/04; A61P11/04; A61P11/14; C07D271/06; C07D273/02; C07D473/06; (IPC1-7): C07D473/06; A61K31/52



 
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