Title:
呼吸器多核体ウイルスプロテインＧのペプチド断片、免疫原的薬剤、それを含む医薬組成物、および製造法
Document Type and Number:
Japanese Patent JPH09511404
Kind Code:
A
Abstract:
New polypeptides (I) useful as immunogenic elements comprise a peptide sequence between amino acids 130 and 230 of the protein G sequence of respiratory syncytial virus (RSV) subgroup A or B, or a sequence having at least 80% homology with this sequence. Also claimed are: (1) an immunogenic agent comprising a polypeptide (I) coupled to a carrier protein; (2) a compsn. for preventing and/or treating RSV subgroup A and/or B infections contg. a polypeptide (I) or an immunogenic agent as in (1); (3) a nucleotide sequence coding for a polypeptide (I); (4) a protein (namely Klebsiella pneumoniae p40 protein) with a defined sequence of 335 amino acids given in the specification, or with 80% homology with this sequence; (5) a nucleotide sequence coding for K.pneumoniae p40 protein; and (6) a process for preparing a peptide conjugate for use in the compsn. of (2).
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Inventors:
トルデル, Michael
ヌグイアン, knock ティアン
ビンツ, Hans
ボサン, Thierry
ヌグイアン, knock ティアン
ビンツ, Hans
ボサン, Thierry
Application Number:
JP52612395A
Publication Date:
November 18, 1997
Filing Date:
April 06, 1995
Export Citation:
Assignee:
Pierre, Fabre, medicament
International Classes:
C12N15/09; A61K39/155; A61K47/48; A61P31/12; C07H21/04; C07K14/08; C07K14/115; C07K14/135; C07K14/26; C07K14/705; C07K14/765; C07K19/00; C12N15/45; C12P21/02; A61K38/00; C12R1/19; (IPC1-7): C12N15/09; A61K39/155; C07H21/04; C07K14/115; C07K14/705; C07K19/00
Attorney, Agent or Firm:
Sato One male (besides two persons)