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Title:
レトロウイルスベクターハイブリッド及びその遺伝子転移のための使用
Document Type and Number:
Japanese Patent JPH09511405
Kind Code:
A
Abstract:
PCT No. PCT/EP95/03175 Sec. 371 Date Mar. 7, 1997 Sec. 102(e) Date Mar. 7, 1997 PCT Filed Aug. 10, 1995 PCT Pub. No. WO96/07747 PCT Pub. Date Mar. 14, 1996Replication-defective retroviral vector hybrids which are characterized in that they contain a) the U5 region and/or tRNA primer binding site of MESV as the U5 region and/or tRNA primer binding site in the leader region and b) the U3 and R regions from a Friend murine leukaemia virus (F-MuLV) as the U3 and R regions in the 3'-LTR and which are particularly suitable for an effective gene transfer in haematopoietic stem cells.

Inventors:
オスタータグ,ボルファム
ストッキンク−ハーバース,キャロル
バウム,クリストファー
Application Number:
JP50914996A
Publication Date:
November 18, 1997
Filing Date:
August 10, 1995
Export Citation:
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Assignee:
ベーリンガー マンハイム ゲゼルシャフト ミット ベシュレンクテル ハフツング
International Classes:
A61K35/76; A61K48/00; A61P35/00; C07H21/04; C07K14/705; C12N15/09; C12N5/10; C12N15/867; (IPC1-7): C12N15/09; A61K35/76; A61K48/00; C07H21/04; C12N5/10
Attorney, Agent or Firm:
石田 敬 (外3名)