Title:
【発明の名称】選択的かつ非侵襲的な視覚化または脈管構造の処置
Document Type and Number:
Japanese Patent JPH10510807
Kind Code:
A
Abstract:
Disclosed are methods and materials for visualizing or treating vasculature. The methods and materials in this invention relate to selective and non-invasive visualization, or treatment such as chemical occlusion, of vasculature in the mammalian eye. The methods utilize fluorescent dyes and tissue-reactive substances encapsulated within heat-sensitive liposomes which are subsequently heated to release the contents thereof at a pre-determined anatomical locus. The methods of this invention further utilize tissue-reactive agents which, when activated, are effective to cause localized tissue damage and occlusion of blood vessels and/or blood sinuses. The materials of this invention relate to diagnostic reagents and kits for visualizing or treating a mammalian blood vessel or sinus.
Inventors:
Zimmer, Run
Application Number:
JP51884596A
Publication Date:
October 20, 1998
Filing Date:
November 16, 1995
Export Citation:
Assignee:
THE JOHNS HOPKINS UNIVERSITY
International Classes:
A61K41/00; A61K45/06; A61K49/00; A61K9/127; A61P41/00; (IPC1-7): A61K45/06; A61K9/127; A61K41/00
Attorney, Agent or Firm:
Shusaku Yamamoto