Title:
【発明の名称】苦痛を管理しおよび薬物依存性を軽減するための、ケタミンの投与
Document Type and Number:
Japanese Patent JPH11511466
Kind Code:
A
Abstract:
The present invention relates to the management of pain without requiring or allowing for reduction in the level of administration of narcotics, and to self-management of pain on an outpatient basis. Accordingly, the present invention is broadly directed to a method for treating pain in a subject comprising administering via a transmucosal, transdermal, or oral route a dose of ketamine effective to alleviate pain to a subject suffering from pain. The invention is further directed to a method for synergistically treating pain in a subject comprising administering via any route a dose of ketamine effective to allow for reduction in the level of an ongoing pain therapy, or decrease pain (improve the level of pain relief), or both. Transmucosal, transdermal, and oral administration of ketamine advantageously allows for patient self administration of the drug, which provides for pain management on an outpatient basis. Moreover, ketamine administration in transdermal devices (suppositories, candies, buccal patches) is generally socially acceptable. In a specific example, a patient suffering from intractable bladder pain controlled breakthrough pain by transmucosal (nasal) administration of about 16 mg to about 32 mg of ketamine per dose.
Inventors:
Weg Stuart El
Application Number:
JP51063697A
Publication Date:
October 05, 1999
Filing Date:
August 29, 1996
Export Citation:
Assignee:
Weg Stuart El
International Classes:
A61K31/00; A61K31/135; A61P23/00; A61P43/00; (IPC1-7): A61K31/135; A61K31/00
Attorney, Agent or Firm:
Minoru Nakamura (6 outside)
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