- Patent JPS6234040

Document Type and Number:

Japanese Patent JPS6234040

Kind Code:

B2

Abstract:

Corticoid-21-sulphopropionate derivs. of formula (I) and their salts with pharmaceutically-acceptable bases are new: (St = steroid residue of an antiinflammatory corticoid; esp. it has formula (X = H, Cl, F or CH3; Y = H, F or Cl; Z = oxo or (alpha-H, beta-OH) U-V is CH2CH2, CH=CH or R1 = H, OH or 1-8C acyloxy; R2 = H or CH3; R3 and R4 = 1-4C alkyl; and underscored ...... is a single or double bond). (I) are readily soluble in water giving conc. solns. which can be sterilized by heating and stored, and are converted rapidly to the free corticoid following injection.

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Inventors:

HENRII RAURENTO
PEETAA ESUPAARINGU
YOAHIMU FURIIDORITSUHI KATSUPU
RUDORUFU UIIHIERUTO

Application Number:

JP12742479A

Publication Date:

July 24, 1987

Filing Date:

October 04, 1979

Export Citation:

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Assignee:

SCHERING AG

International Classes:

C12P33/18; A61K31/57; A61K31/58; A61K35/58; A61P5/38; A61P29/00; A61P37/08; C07J5/00; C07J31/00; C07J41/00; C07J51/00; C07J53/00; C07J63/00; C07J71/00; C12P33/08

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