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Document Type and Number:
Japanese Patent JPS6239160
Kind Code:
B2
Abstract:
Novel 7-alkyl- DELTA 4-17 alpha -pregnene-3-ones of the formula I wherein R is selected from the group consisting of saturated and unsaturated alkyl of 2 to 8 carbon atoms, cycloalkyl alkyl of 4 to 8 carbon atoms and arylalkyl of 7 to 12 carbon atoms and X and Y form the group or X is OH and Y is and M is selected from the group consisting of hydrogen, alkali metal and NH4 and the wavy line indicates the alpha - or beta -position or mixtures thereof having aldosterone antagonistic activity and increased hydrosodium diuresis with organic potassium conservation while devoid of secondary hormonal effects and their preparation.

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Inventors:
RYUSHIAN NEDOREKU
BESUPERUTO TORERI
ROBEERU FUURUNEKUSU
KORETSUTO TORUNUMIINU
Application Number:
JP3486180A
Publication Date:
August 21, 1987
Filing Date:
March 21, 1980
Export Citation:
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Assignee:
ROUSSEL UCLAF
International Classes:
A61K31/565; A61K31/575; A61K31/585; A61P5/38; A61P9/00; A61P9/12; C07J1/00; C07J9/00; C07J21/00; C07J51/00



 
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