Title:
【発明の名称】線維芽細胞発育因子
Document Type and Number:
Japanese Patent JPS63500036
Kind Code:
A
Abstract:
Substantially pure basic fibroblast growth factor (bFGF), a 146 amino acid residue polypeptide, is produced. The amino acid residue sequence of bFGF is disclosed as well as a DNA chain encoding the polypeptide. By appropriately inserting a synthesized DNA chain into a cloning vector and using the cloning vector to transform cells, synthetic bFGF can be obtained from transformed cell lines, both prokaryotic and eukaryotic.
Inventors:
Esh, Frederick Stephen
Andrew, Bayad
Beaulen, Peter
Gospodarowitz, Dennis Jersey
Ring, Nicholas Chai-Kwan
Andrew, Bayad
Beaulen, Peter
Gospodarowitz, Dennis Jersey
Ring, Nicholas Chai-Kwan
Application Number:
JP50356986A
Publication Date:
January 07, 1988
Filing Date:
June 18, 1986
Export Citation:
Assignee:
The Salk Institute For Biological Studies
International Classes:
C07K14/00; C07K14/50; C12N1/16; C12N1/19; C12N1/20; C12N1/21; C12N15/00; C12N15/09; C12N15/12; C12P21/02; A61K38/00; C12R1/19; C12R1/865; C12R1/91; (IPC1-7): C12R1/865; C12R1/19; C12P21/02; C12N15/00; C12N1/20; C12N1/16; C07K13/00
Attorney, Agent or Firm:
Kyozo Yuasa