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Document Type and Number:
Japanese Patent JPS641474
Kind Code:
B2
Abstract:
Novel alpha -fluoromethyl- alpha -amino acids and esters have the following formula in which R is a substituted C1-C4-alkyl group and R1 has the meaning of H or C1-C18-alkyl. The compounds can be present as acid addition salts. The compounds of the formula I, as well as their pharmaceutically acceptable acid addition salts, are used as active compounds in medicaments which have a decarboxylase-inhibiting effect. Processes for preparing the novel compounds are described.

Inventors:
JANOSU KORONITSUSHU
SUTEFUEN MAARUBURUGU
AASAA ARAN PACHETSUTO
Application Number:
JP6501678A
Publication Date:
January 11, 1989
Filing Date:
June 01, 1978
Export Citation:
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Assignee:
MERCK & CO INC
International Classes:
A61K31/195; A61K31/215; A61K31/22; A61K31/403; A61K31/404; A61K31/405; A61K31/415; A61P9/12; A61P43/00; C07C67/00; C07C227/00; C07C227/16; C07C229/20; C07C229/24; C07C229/36; C07C239/00; C07C279/14; C07C313/00; C07C323/12; C07D209/20; C07D233/54; C07D233/64



 
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