Title:
ＣＡＰ結合蛋白質
Document Type and Number:
Japanese Patent JPWO2004033688
Kind Code:
A1
Abstract:
A novel polypeptide which is useful in screening of an agent for improving insulin resistance and an agent for improving glucose metabolism, a polynucleotide encoding the polypeptide, an expression vector comprising the polynucleotide, and a cell transformed with the expression vector are disclosed. The polypeptide is a protein expressed in skeletal muscle. When the protein is overexpressed, incorporation of sugar into a cell is inhibited. A method for screening of an agent for improving insulin resistance and/or an agent for improving glucose metabolism in which the polypeptide is used, and a method for producing a pharmaceutical composition for insulin resistance and/or glucose metabolism improvement comprising a substance obtained according to the method for screening as an active ingredient are also disclosed.
Inventors:
小田 環
遠藤 英樹
上田 能孝
井鍋 一則
遠藤 英樹
上田 能孝
井鍋 一則
Application Number:
JP2004542859A
Publication Date:
February 09, 2006
Filing Date:
October 09, 2003
Export Citation:
Assignee:
アステラス製薬株式会社
International Classes:
C12N15/09; A61K45/00; A61P3/10; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12Q1/02; A61K38/00