1,2-DIHYDROPYRIDINE COMPOUND, METHOD FOR PRODUCING THE SAME AND USE THEREOF

Japanese Patent JP2012207021

A

To provide a new compound having an excellent AMPA receptor inhibitory action and/or kainate receptor inhibitory action.

The compound is represented by formula (II), a salt thereof or hydrates thereof. [wherein, Q indicates O; X¹, X² and X³ are each indicates a single bond; A¹, A² and A³ are the same as or different from each other and each a (substituted) 3-8C cycloalkyl group, 3-8C cycloalkenyl group, 5-14 membered non-aromatic heterocyclic group, 6-14C aromatic hydrocarbon group or 5-17 membered aromatic heterocyclic group; R¹⁷ and R¹⁸ are the same as or different from each other and indicates a hydrogen atom, a halogen atom, or a 1-6C alkyl group].

NAGATO SATORU
UENO TSUGUSHI
KAWANO KOKI
NORIMINE YOSHIHIKO
ITO KOICHI
HANADA YOSHIHISA
UENO MASATAKA
AMINO HIROYUKI
OSATO MAKOTO
HATAKEYAMA SHINJI
URAWA YOSHIO
NAKA HIROYUKI
GROOM ANTHONY JOHN
RIVERS LEANNE
SMITH TERENCE

JP2012115592A

October 25, 2012

May 21, 2012

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EISAI R&D MAN CO LTD

C07D213/64; A61K31/4412; A61K31/443; A61K31/4433; A61K31/4436; A61K31/444; A61K31/4709; A61K31/496; A61K31/501; A61K31/506; A61P1/08; A61P9/10; A61P13/02; A61P21/04; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/28; A61P25/30; A61P43/00; B01J23/44; B01J27/122; B01J31/02; B01J31/04; B01J31/24; C07D213/65; C07D213/69; C07D213/70; C07D213/73; C07D213/74; C07D213/75; C07D213/76; C07D213/81; C07D213/84; C07D213/89; C07D401/04; C07D401/14; C07D405/04; C07D405/14; C07D409/04; C07D409/14; C07D413/04; C07D413/14; C07D417/04; C07D417/14; C07D471/04; C07D471/06; C07F7/18; C07B61/00; A61K; A61P; C07D

Satoshi Furuya
Takahiko Mizobe
Yoshitsune Kazumasa

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