Title:
TNF-アルファの生産を阻害する2-シクロペンテン-1-オンオキシム誘導体
Document Type and Number:
Japanese Patent JP4903155
Kind Code:
B2
Abstract:
2-cyclopenten-1-one oxime derivatives represented by Formula (I), or pharmaceutically acceptable salts thereof inhibit the production of TNF-α or PDE4, and therefore show therapeutic effect in inflammatory or immunological disorders mediated through TNF-α or PDE4.
Inventors:
Kim Young Joon
Kim Seung Young
Hwang Jun Soon
Lim Kyung Min
Park Mi Young
Ko Hyunju
Hong Sa Young
Shin Sung Suk
Choi Jinkyu
Mo Joe Hyun
Chun Singh
Wu Byung-young
Kim Seung Yi
Kim Seung Young
Hwang Jun Soon
Lim Kyung Min
Park Mi Young
Ko Hyunju
Hong Sa Young
Shin Sung Suk
Choi Jinkyu
Mo Joe Hyun
Chun Singh
Wu Byung-young
Kim Seung Yi
Application Number:
JP2007544262A
Publication Date:
March 28, 2012
Filing Date:
November 30, 2005
Export Citation:
Assignee:
AMOREPACIFIC CORPORATION
International Classes:
C07C251/44; A61K31/15; A61K31/155; A61K31/166; A61K31/192; A61K31/235; A61K31/277; A61K31/343; A61K31/36; A61K31/381; A61K31/385; A61K31/404; A61K31/4406; A61P1/04; A61P1/16; A61P3/10; A61P7/00; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P31/04; A61P37/02; A61P37/08; A61P43/00; C07C255/64; C07C259/14; C07C317/32; C07C323/47; C07D209/08; C07D213/53; C07D307/91; C07D317/58; C07D333/22; C07D333/58; C07D339/08
Domestic Patent References:
| JP8511031A |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Samejima Mutsumi
Nagatoshi Shinagawa