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Title:
2-AMINOPYRIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS
Document Type and Number:
Japanese Patent JP2015025014
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide 2-aminopyridine derivatives useful as kinase inhibitors.SOLUTION: The present invention relates to compounds represented by the structural formula (I) useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising the compounds and methods of using the compositions in treatment of various disease, conditions or disorders. The invention also provides methods for preparing compounds of the inventions. In one embodiment, the invention provides a method of treating or preventing a protein kinase-mediated condition in a subject.

Inventors:
JUAN-MIGUEL JIMENEZ
BEMIS GUY
MAKTAIS FRANCOIS
WANG TIANSHENG
KNEGTEL RONALD
DAVIS CHRIS
FRAYSSE DAMIEN
BOYALL DEAN
SETTIMO LUCA
YOUNG STEVEN
MORTIMORE MICHAEL
Application Number:
JP2014219913A
Publication Date:
February 05, 2015
Filing Date:
October 29, 2014
Export Citation:
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Assignee:
VERTEX PHARMA
International Classes:
C07D213/38; A61K31/4436; A61K31/4439; A61K31/444; A61K31/496; A61K31/4985; A61K31/4995; A61K31/5377; A61K31/55; A61K31/551; A61K31/553; A61P1/04; A61P3/10; A61P7/00; A61P9/00; A61P19/02; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P43/00; C07D213/73; C07D213/74; C07D401/06; C07D401/14; C07D405/14; C07D409/06; C07D409/14; C07D413/14; C07D417/06; C07D417/14; C07D487/04; C07D487/08; C07D495/04
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita