4- OR 5-SUBSTITUTED PYRROLE DERIVATIVE

Title:

4- OR 5-SUBSTITUTED PYRROLE DERIVATIVE

Document Type and Number:

Japanese Patent JP2002284780

Kind Code:

A

Abstract:

To obtain a compound capable of controlling production of inflammatory cytokine.

This compound is represented by general formula (I) {A is pyrrole; R1 is a substitutable aryl or a substitutable heteroaryl; R2 is a substitutable heteroaryl; R3 is a bicyclic amino group; R4 and R5 are each H, a substituted cycloalkyl, a substitutable aryl, a substitutable heteroaryl or a substitutable heterocyclyl; with the proviso that atoms on the pyrrole ring to which R1 and R3 are bonded are adjacent to an atom on the pyrrole ring to which R2 is bonded, respectively} or its pharmacologically acceptable salt, ester or other derivative.

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Inventors:

KIMURA TOMIO
OKAWA NOBUYUKI
AOKI KAZUMA

Application Number:

JP2002012243A

Publication Date:

October 03, 2002

Filing Date:

January 22, 2002

Export Citation:

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Assignee:

SANKYO CO

International Classes:

A61K31/444; A61K31/4545; A61P1/00; A61P1/16; A61P3/10; A61P7/00; A61P9/10; A61P11/06; A61P13/12; A61P17/06; A61P19/02; A61P19/10; A61P25/28; A61P29/00; A61P31/12; A61P35/00; A61P37/02; A61P37/08; C07D471/04; C07D401/14; (IPC1-7): C07D401/14; A61K31/444; A61K31/4545; A61P1/00; A61P1/16; A61P3/10; A61P7/00; A61P9/10; A61P11/06; A61P13/12; A61P17/06; A61P19/02; A61P19/10; A61P25/28; A61P29/00; A61P31/12; A61P35/00; A61P37/02; A61P37/08; C07D471/04

Attorney, Agent or Firm:

Akio Ohno (4 outside)

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