Title:
4-置換安息香酸誘導体およびそれを有効成分として含有する制癌剤
Document Type and Number:
Japanese Patent JP4125868
Kind Code:
B2
Abstract:
Novel compounds represented by general formula (I) which do not act on normal cells but detransform specifically cells transformed by various oncogenes, salts thereof, or hydrates of the same, wherein G1 represents OR<1> or NR<2>R<3> (wherein R<2> and R<3> are the same or different and each represents hydrogen, lower alkyl or hydroxy, or R<2> and R<3> may form together with the nitrogen atom adjacent thereto a nitrogen-containing heterocycle); G2 represents hydrogen or halogeno; when G3 is hydrogen, hydroxy or lower alkylcarbonyloxy, then G4 represents lower alkyl, or G3 and G4 may form together -O-CH2-; and G5 represents OR<4> or NR<5>R<6> (wherein R<5> represents hydroxy or an optionally substituted cyclic group; and R<6> represents hydrogen or lower alkyl).
Inventors:
Nobuhiro Haga
Kenji Sugita
Susumu Kamada
Kenji Sugita
Susumu Kamada
Application Number:
JP2000510697A
Publication Date:
July 30, 2008
Filing Date:
September 07, 1998
Export Citation:
Assignee:
Shionogi Pharmaceutical Co., Ltd.
International Classes:
C07C65/40; A61K31/165; A61K31/19; A61K31/235; A61P35/00; C07C69/94; C07C229/52; C07C235/84; C07C237/40; C07C259/10; C07D207/16; C07D309/08
Domestic Patent References:
| JP3291264A | ||||
| JP6110528A |
Other References:
Journal of the American Chemical Society,1949年,71,2132-7
Attorney, Agent or Firm:
Hideaki Yamauchi
Kenichi Sugita
Kenichi Sugita