Title:
5R,6S-6-(1R-HYDROXYETHYL)-2-(CIS-1-OXO-3- THIOLANYLTHIO)-2-PENEM-3-CARBOXYLIC ACIDS OF DIASTEREOMER
Document Type and Number:
Japanese Patent JPS63287781
Kind Code:
A
Abstract:
Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(1S-oxo-3R-thiolanylthio )-2-penem-3-carboxylic acid and 5R,6S-6-(1R-hydroxyethyl)-2-(1R-oxo-3S-thiolanylthio )-2-penem-3-carboxylic acid, and pharmaceutically-acceptable salts and in vivo hydrolyzable esters thereof, useful as systemic antibacterial agents; and intermediates and processes which are useful in the said synthesis of said diastereoisomers.
Inventors:
ROBAATO ARUFURETSUDO BORUKUMAN
Application Number:
JP11171788A
Publication Date:
November 24, 1988
Filing Date:
May 10, 1988
Export Citation:
Assignee:
PFIZER
International Classes:
A61K31/397; A61K31/43; A61P31/04; C07D301/26; C07D303/12; C07D303/16; C07D333/16; C07D205/09; C07D333/18; C07D333/28; C07D333/32; C07D333/34; C07D333/48; C07D409/12; C07D499/86; C07D499/88; C07D499/897; (IPC1-7): A61K31/43; C07D205/08; C07D303/12; C07D333/16; C07D333/18; C07D333/48; C07D499/00
Domestic Patent References:
| JPS6299379A | 1987-05-08 |
Attorney, Agent or Firm:
Heikichi Odashima
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