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Title:
9α-ヒドロキシ-ステロイドの合成方法
Document Type and Number:
Japanese Patent JP2010531660
Kind Code:
A
Abstract:
The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)—wherein the meaning of -A-A′- is —CH2—CH2— or —CH═CH— group—by the bioconversion of compounds of the general formula (II) (II) wherein the meaning of -A-A′- is —CH2—CH2— or —CH═CH— group—by using Nocardia farcinica bacterium strain, deposition number of which is NCAIM (P)—B 001342, as hydroxylating microorganism in the bioconversion.

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Inventors:
Katharine Olas
Aniko Tegdes
Valeria Gurnchos
Garbol Huntos
Kalman Kenchel
Garbol Balog
Saunder Elderei
Application Number:
JP2010514150A
Publication Date:
September 30, 2010
Filing Date:
June 30, 2008
Export Citation:
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Assignee:
Richter Gedeon Nyrt.
International Classes:
C12P33/06; C12N15/09
Foreign References:
WO1997021720A21997-06-19
US4397947A1983-08-09
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka



 
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