Title:
AKT活性阻害剤
Document Type and Number:
Japanese Patent JP2008510823
Kind Code:
A
Abstract:
The present invention is directed to compounds which contain substituted 5-deazapteridine moieties which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
Inventors:
Bilodo, Mark Tay
Kosuf Aude, Nicholas Day Pee
Heartnet, Jiyoung Shee
Lian, Chiyun
Manley, peter theay
Neilson, Lou Ann
Siu, Tony
Woo Ji Kai
Lee, Eway
Kosuf Aude, Nicholas Day Pee
Heartnet, Jiyoung Shee
Lian, Chiyun
Manley, peter theay
Neilson, Lou Ann
Siu, Tony
Woo Ji Kai
Lee, Eway
Application Number:
JP2007530047A
Publication Date:
April 10, 2008
Filing Date:
August 19, 2005
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D471/04; A61K31/519; A61P35/00; C07D519/00
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura