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Title:
ヒストンデアセチラーゼのインヒビターとしてのアセチレン誘導体
Document Type and Number:
Japanese Patent JP2007502838
Kind Code:
A
Abstract:
The present invention is directed to certain hydroxamate derivatives that are inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.

Inventors:
Sendzig, Martin
Application Number:
JP2006524072A
Publication Date:
February 15, 2007
Filing Date:
August 19, 2004
Export Citation:
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Assignee:
AXYS PHARMACEUTICALS, INC.
International Classes:
C07C259/10; A61K31/17; A61K31/19; A61K31/343; A61K31/351; A61K31/381; A61K31/404; A61K31/4184; A61K31/421; A61K31/426; A61K31/4525; A61K31/454; A61K31/47; A61K31/5377; A61P1/16; A61P7/00; A61P9/10; A61P11/02; A61P11/06; A61P17/06; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07C271/02; C07C275/28; C07C275/30; C07C275/32; C07C311/19; C07D209/42; C07D215/16; C07D215/48; C07D231/12; C07D235/24; C07D239/70; C07D261/08; C07D263/34; C07D277/20; C07D277/56; C07D277/68; C07D307/85; C07D333/38; C07D333/70; C07D333/72; C07D401/12; C07D405/12; C07D407/12
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaya Nishiyama