Title:
アルキンマトリックスメタロプロテイナーゼ阻害剤
Document Type and Number:
Japanese Patent JP4164028
Kind Code:
B2
Abstract:
A compound of Formula Ior a pharmaceutically acceptable salt thereof, or a tautomer thereof, wherein G1, G2, and B are as defined in the application, are selective inhibitors of MMP-13. The compounds are useful for treating diseases mediated by MMP-13, including cancer and arthritis.
Inventors:
Amy May Bunker
William Glen Harter
James Lester Hicks
Patrick Mikle O'Brien
Ry sea femme
Joseph Armand Picard
William Howard Rourke
William Glen Harter
James Lester Hicks
Patrick Mikle O'Brien
Ry sea femme
Joseph Armand Picard
William Howard Rourke
Application Number:
JP2003535802A
Publication Date:
October 08, 2008
Filing Date:
August 02, 2002
Export Citation:
Assignee:
Warner-Lambert Company Limited Liability Company
International Classes:
C07C233/87; A61K31/18; A61K31/195; A61K31/277; A61K31/4192; A61K31/4196; A61K31/4409; A61K31/455; A61K31/5415; A61P1/00; A61P1/02; A61P9/04; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/08; A61P19/10; A61P29/00; A61P35/00; A61P43/00; C07C235/42; C07C255/57; C07C255/60; C07C311/39; C07C311/46; C07C317/32; C07D213/40; C07D213/56; C07D213/64; C07D213/81; C07D213/82; C07D215/233; C07D249/04; C07D249/08; C07D279/02; C07D285/16; C07D285/24; C07D291/08; C07D401/06; C07D495/04; C07D513/04; C07D515/04; C07D521/00; C07D215/22
Domestic Patent References:
| JP2005503327A | ||||
| JP2005509626A | ||||
| JP2004523546A |
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa