Title:
アミロイドーシスを治療するためのアミジン誘導体
Document Type and Number:
Japanese Patent JP2007518786
Kind Code:
A
Abstract:
The present invention relates to the use of amidine compounds in the treatment of amyloid-related diseases. In particular, the invention relates to a method of treating or preventing an amyloid-related disease in a subject comprising administering to the subject a therapeutic amount of an amidine compound. Among the compounds for use according to the invention are those according to the following Formula (I), such that, when administered, amyloid fibril formation, neurodegeneration, or cellular toxicity is reduced or inhibited: Formula (I).
Inventors:
Conscious
Wu Shinfu
Minyo David
Wu Shinfu
Minyo David
Application Number:
JP2006550316A
Publication Date:
July 12, 2007
Filing Date:
January 23, 2004
Export Citation:
Assignee:
Neurochem (International) Limited
International Classes:
C07C257/18; A61K31/155; A61K31/166; A61K31/167; A61K31/18; A61K31/216; A61K31/4164; A61K31/4168; A61P3/10; A61P5/50; A61P25/28; A61P27/02; A61P43/00; C07C259/18; C07C311/18; C07D233/22; C07D233/50
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi