EDG受容体作動薬としてのアミノアルキルホスホネートおよび関連化合物

Japanese Patent JP2005531508

A

The present invention encompasses compounds of Formula II: as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

Doherty, Giyo A
Hale, Jefrey Jay

JP2003572530A

October 20, 2005

February 25, 2003

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MERCK & COMPANY INCOPORATED

A61K31/18; A61K31/197; A61K31/41; A61K31/4164; A61K31/4192; A61K31/4196; A61K31/661; A61K31/662; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P3/04; A61P3/10; A61P5/14; A61P7/06; A61P9/10; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P17/10; A61P17/14; A61P19/10; A61P21/04; A61P25/00; A61P25/06; A61P27/02; A61P27/16; A61P29/00; A61P31/04; A61P31/14; A61P31/18; A61P31/20; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P37/08; C07C229/34; C07C233/11; C07C309/24; C07C311/51; C07D233/84; C07D249/04; C07D249/12; C07D257/04; C07D257/06; C07F9/09; C07F9/38; (IPC1-7): C07C229/34; A61K31/18; A61K31/197; A61K31/41; A61K31/4164; A61K31/4192; A61K31/4196; A61K31/661; A61K31/662; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P3/04; A61P3/10; A61P5/14; A61P7/06; A61P9/10; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P17/10; A61P17/14; A61P19/10; A61P21/04; A61P25/00; A61P25/06; A61P27/02; A61P27/16; A61P29/00; A61P31/04; A61P31/14; A61P31/18; A61P31/20; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P37/08; C07C233/11; C07C309/24; C07C311/51; C07D233/84; C07D249/04; C07D249/12; C07D257/04; C07D257/06; C07F9/09; C07F9/38

Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura

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