Title:
アミロイド結合ペプチド、類似体及びその使用
Document Type and Number:
Japanese Patent JP2008530194
Kind Code:
A
Abstract:
The present invention relates to chemical compounds and compositions comprising amyloid-binding peptide sequences, or analogues and derivatives thereof, which bind to a target amyloid-forming protein or peptide. The amyloid-binding peptide sequences are not essentially derived from or otherwise based on any section of the target amyloid-forming protein or peptide, and they comprise a minimum number of non-natural amino acid side chains. The chemical compounds and compositions are useful for the diagnosis and treatment of diseases and disorders associated with a fundamental pathogenic process of protein or peptide misfolding and aggregation, called "amyloidosis".
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Inventors:
Stott, Kelvin
Andrew, Doig
Trehan, Mark
Scopes, David
Andrew, Doig
Trehan, Mark
Scopes, David
Application Number:
JP2007555695A
Publication Date:
August 07, 2008
Filing Date:
February 16, 2006
Export Citation:
Assignee:
Senex Limited
International Classes:
C07K7/06; A61K38/00; A61P3/00; A61P3/10; A61P5/14; A61P13/08; A61P21/00; A61P21/04; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P31/12; A61P35/00; A61P43/00; C07K5/083; C07K5/087; C07K5/103; C07K5/107; C07K5/117; C07K14/47
Attorney, Agent or Firm:
Yoshio Ishii
Kyoko Yoshimi
Sanae Goto
Kiyoshi Fujino
Kyoko Yoshimi
Sanae Goto
Kiyoshi Fujino