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Title:
ANILINOQUINAZOLINE COMPOUND AND ITS USE
Document Type and Number:
Japanese Patent JP2008255098
Kind Code:
A
Abstract:

To provide a compound showing anticancer and antitumor activity through a novel action mechanism, and a medicine composition containing the compound.

This invention relates to an anilinoquinazoline compound represented by the formula or its salt, and this drug composition contains the compound or its salt. The compound exerts the anticancer activity by a novel action mechanism which is different from that of current compounds (for example, paclitaxel, docetaxel, gefitinib, and taxol). Therefore, it is possible to provide a composition for curing cancer having little side-effect by using the compound by itself or in combination with other anticancer drugs.


Inventors:
KIMURA HIRONOBU
TAKASHIMA HIDEAKI
YANAGAWA HIROSHI
KITANO YASUNORI
NAKANO HIROSHI
Application Number:
JP2008041430A
Publication Date:
October 23, 2008
Filing Date:
February 22, 2008
Export Citation:
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Assignee:
KEIO GIJUKU
International Classes:
C07D239/94; A61K31/517; A61P35/00; C12N15/09
Domestic Patent References:
JP2005501796A2005-01-20
JP2003524006A2003-08-12
Foreign References:
WO2006124692A22006-11-23
Other References:
JPN6013009228; Current Biology Vol.15, No.7, 2005, pp.R265-R275
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Tsutomu Toyama