Title:
上皮成長因子受容体の欠失型変異体を認識する抗体、およびそれらの使用
Document Type and Number:
Japanese Patent JP4800210
Kind Code:
B2
Abstract:
The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.
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Inventors:
Richard Wee-Bar
Xiao Feng
Orit Ford
Rally green
Gene Gudas
Bruce Quito
Ing Liu
Parani Rasana Swami
Robert Raya
Xiao Dong Young
Jose Corvallan
Ian Fortz
Xiao-Ji Jia
Jaspar can
Chadwick Tea King
Scott El Cracamp
Cao Juan Jane Su
Xiao Feng
Orit Ford
Rally green
Gene Gudas
Bruce Quito
Ing Liu
Parani Rasana Swami
Robert Raya
Xiao Dong Young
Jose Corvallan
Ian Fortz
Xiao-Ji Jia
Jaspar can
Chadwick Tea King
Scott El Cracamp
Cao Juan Jane Su
Application Number:
JP2006517700A
Publication Date:
October 26, 2011
Filing Date:
June 25, 2004
Export Citation:
Assignee:
Am Jien Fremont Incorporated
International Classes:
C07K16/28; A61K39/395; A61K47/48; A61P35/00; C07K16/22; C07K17/00; C12N5/06; C12N15/02; C12N15/09; G01N33/53; G01N33/574; C12P21/08; C12N
Foreign References:
| WO1998050433A2 | 1998-11-12 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro