ANTITUMOR AGENT - KYOWA HAKKO KOGYO KK

Title:

ANTITUMOR AGENT

Document Type and Number:

Japanese Patent JPS5925330

Kind Code:

A

Abstract:

PURPOSE: To provide a carcinostatic agent containing actinomycin S3 as an active component.

CONSTITUTION: Actinomycin D and actinomycin S3 having antibacterial activity can be obtained from the cultured product of a bacterial strain KY 11634 (FERM-P No.4673). Actinomycins known as antibiotics include actinomycin D, C, C2, S3, etc. The actinomycin S3 (LD50: 0.35mg/kg, i.p.) having higher activity than the actinomycin D having antitumor activity is used as an active component for a carcinostatic agent. It is administered by intravenous injection, peritoneal infusion, etc. Preferable doses for intravenous injection or peritoneal infusion: 2W4μg/kg daily for continuous administration and 10W15μg/kg per dose for intermittent administration (once/7 days).

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Inventors:

TOMITA FUSAO
TAMAOKI TATSUYA
OOKUBO SHIYUUJI

Application Number:

JP12437783A

Publication Date:

February 09, 1984

Filing Date:

July 08, 1983

Export Citation:

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Assignee:

KYOWA HAKKO KOGYO KK

International Classes:

A61K38/00; A61K35/74; A61P35/00; (IPC1-7): A61K35/74; A61K37/02

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