Title:
BENZAMIDE DERIVATIVE AND ITS UTILIZATION
Document Type and Number:
Japanese Patent JP2002241273
Kind Code:
A
Abstract:
To provide a compound which inhibits FXR transcription activity and is useful for treating hyperlipemia.
This FXR transcription activity inhibitor contains the compound represented by the formula [R1 is an alkyl, an alkenyl, phenyl, or the like, which may be substituted, respectively; R2 is H or an alkyl which may be substituted; R3 and R4 are each independently H, hydroxyl or an alkoxy which may be substituted; R5 and R6 are each independently H or an alkyl which may be substituted; provided that a case where R1 is phenyl; R2 is H; R3 and R4 are each OH; and R5 and R6 are each tert-butyl is excluded] or its medicinally acceptable salt.
Inventors:
UENO YOSHIHIDE
SAWADA NOBUYUKI
HASEGAWA HIROHIKO
SAWADA NOBUYUKI
HASEGAWA HIROHIKO
Application Number:
JP2001035288A
Publication Date:
August 28, 2002
Filing Date:
February 13, 2001
Export Citation:
Assignee:
SUMITOMO PHARMA
International Classes:
C07D295/14; A61K31/166; A61K31/341; A61K31/381; A61K31/40; A61K31/403; A61K31/4035; A61K31/404; A61K31/415; A61K31/4184; A61K31/4245; A61K31/426; A61K31/428; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/4458; A61K31/4462; A61K31/454; A61K31/47; A61K31/5355; A61K31/5375; A61K31/5377; A61P3/06; A61P43/00; C07C233/25; C07C233/27; C07C233/29; C07C233/60; C07C233/75; C07C233/88; C07C235/16; C07C235/56; C07C235/64; C07C237/04; C07C237/40; C07C255/57; C07C321/14; C07D207/34; C07D209/08; C07D209/42; C07D211/60; C07D213/81; C07D213/82; C07D215/48; C07D215/54; C07D231/14; C07D235/08; C07D271/12; C07D277/64; C07D307/68; C07D333/38; C07D333/70; (IPC1-7): A61K31/166; A61K31/341; A61K31/381; A61K31/40; A61K31/4035; A61K31/415; A61K31/4184; A61K31/4245; A61K31/426; A61K31/428; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/4458; A61K31/4462; A61K31/47; A61K31/5375; A61P3/06; A61P43/00; C07C233/25; C07C233/27; C07C233/29; C07C233/60; C07C233/75; C07C233/88; C07C235/16; C07C235/56; C07C235/64; C07C237/04; C07C237/40; C07C255/57; C07C321/14; C07D207/34; C07D209/08; C07D209/42; C07D211/60; C07D213/81; C07D213/82; C07D215/48; C07D215/54; C07D231/14; C07D235/08; C07D271/12; C07D277/64; C07D295/14; C07D307/68; C07D333/38; C07D333/70
Attorney, Agent or Firm:
Toshio Nakamura