Title:
BROAD SPECTRUM β-LACTAMASE INHIBITORS
Document Type and Number:
Japanese Patent JP2015155435
Kind Code:
A
Abstract:
【課題】強力な抗菌活性を示す、広帯域スペクトルβ−ラクタマーゼ阻害薬の提供。【解決手段】化合物は、β−ラクタム環の開裂により、β−ラクタマーゼを不活性化できる反応性部分を生じる様に設計された式（Ｉ）で表される化合物。前記阻害を示すβ−ラクタマーゼ阻害薬の製造方法及びβ−ラクタム系抗生物質。更に、細菌感染症を治療又は予防するための医薬組成物、及び前記感染症の治療方法。【選択図】図２
Inventors:
LARRY SUTTON
YU SOPHIA
YU SOPHIA
Application Number:
JP2015081763A
Publication Date:
August 27, 2015
Filing Date:
April 13, 2015
Export Citation:
Assignee:
SOPHARMIA INC
International Classes:
C07D501/18; A61K31/545; A61K31/546; A61P31/04; A61P43/00; C07D501/22
Domestic Patent References:
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Other References:
BIOORGANIC AND MED. CHEM. LETT., vol. Vol.3(11), JPN6013035363, 1993, pages 2231 - 2236
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THE JOURNAL OF ANTIBIOTICS, vol. Vol.40(7), JPN6016004097, 1987, pages 991 - 1005
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Ikeda adult
Masakazu Noda
Ikeda adult
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