Title:
配位子に促進された触媒不斉ジヒドロキシル化
Document Type and Number:
Japanese Patent JP3153540
Kind Code:
B2
Abstract:
An osmium-catalyzed method of addition to an olefin. In the method of asymmetric dihydroxylation of the present invention, an olefin, a chiral ligand, an organic solvent, water, an amine oxide, an osmium-containing compound and, optionally a tetraalkyl ammonium compound are combined. In the method of asymmetric oxyamination of the present invention, an olefin, a chiral ligand, an organic solvent, water, a metallochloramine derivative, an osmium-containing compound and, optionally, a tetraalkyl ammonium compound are combined. In the method of asymmetric diamination of the present invention, an olefin, a chiral ligand, an organic solvent, a metallochloramine derivative, an amine and an osmium-containing compound are combined. In one embodiment, an olefin, a chiral ligand which is a dihydroquinidine derivative or a dihydroquinine derivative, acetone, water, N-methyl morpholine N-oxide and osmium tetroxide are combined to effect asymmetric dihydroxylation of the olefin.
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Inventors:
シャープレス，ケー・バリー
マルコ，イストヴァン・イー
マルコ，イストヴァン・イー
Application Number:
JP50181489A
Publication Date:
April 09, 2001
Filing Date:
January 10, 1989
Export Citation:
Assignee:
マサチューセッツ・インスティチュート・オブ・テクノロジー
International Classes:
B01J31/22; C07B41/02; C07B43/04; C07B53/00; C07B61/00; C07C29/48; C07C31/20; C07C31/27; C07C31/42; C07C33/26; C07C33/46; C07C35/21; C07D453/04; C07C43/164; C07C43/215; C07C43/23; C07C67/31; C07C69/18; C07C201/12; C07C205/19; C07C213/00; C07C215/34; C07C271/16; C07F7/18; C07F15/00; (IPC1-7): C07B53/00; B01J31/22; C07B41/02; C07B61/00; C07C29/48; C07C31/20; C07C33/26; C07C43/164; C07C69/18; C07C213/00; C07C215/34; C07D453/04
Other References:
Ｃｈｅｍ．Ｒｅｖ．，Ｖｏｌ．８０，Ｎｏ．２，１８７−２１３（１９８０）
Ｊ．Ａｍ．Ｃｈｅｍ．Ｓｏｃ．，Ｖｏｌ．１０２，Ｎｏ．１２，４２６３−５（１９８０）
Ｊ．Ａｍ．Ｃｈｅｍ．Ｓｏｃ．，Ｖｏｌ．１０２，Ｎｏ．１２，４２６３−５（１９８０）
Attorney, Agent or Firm:
津田 淳 （外３名）