Title:
化学修飾された核酸および核酸の固体支持体への結合方法
Document Type and Number:
Japanese Patent JP4477774
Kind Code:
B2
Abstract:
The invention relates to novel chemically modified biological molecules with enhanced lability towards solid supports, such as glass. These modified molecules can be readily affixed to solid supports, for instance, a glass surface, without first derivatizing the glass surface. High-density microarrays based on these modified molecules as well as methods for preparing these microarrays are also useful.
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Inventors:
Bradley Alan
Kai Way Wen
Kai Way Wen
Application Number:
JP2000547274A
Publication Date:
June 09, 2010
Filing Date:
May 04, 1999
Export Citation:
Assignee:
BAYLOR COLLEGE OF MEDICINE
International Classes:
C07H23/00; G01N33/53; C07B61/00; C07H21/00; C12M1/00; C12N15/09; C12Q1/68; C12Q1/6806; G01N37/00; C12Q1/6837
Foreign References:
| WO1997039151A1 | ||||
| WO1996041809A1 |
Other References:
Nucleic Acids Research, 1994, 22, 24, p.5456-5465
Nucleic Acids Research, 1992, 20, 7, p.1679-1684
Molecular Biotechnology, 1995, 4, p.213-225
Nucleic Acids Research, 1992, 20, 7, p.1679-1684
Molecular Biotechnology, 1995, 4, p.213-225
Attorney, Agent or Firm:
Patent Business Corporation Unias International Patent Office