Title:
CHOLESTADIENE DERIVATIVE
Document Type and Number:
Japanese Patent JPH0236192
Kind Code:
A
Abstract:
NEW MATERIAL: Compounds of formula I [wherein R is -COOX (X is H or a 1-8C alkyl) or CH2OH].
EXAMPLE: Methyl 3β-hydroxy-chola-5,23t-diene-24-carboxylate.
USE: Prevention and a remedy of hypercholesterolemia, an HMG-COA reductase inhibitor.
PROCESS: A compound given by formula III is esterified.
Inventors:
BUORUFUGANGU HERUMAN KURAIZAA
PEETAA SHIYARAIN
EANORUTO GURANTSUAA
PEETAA SHIYARAIN
EANORUTO GURANTSUAA
Application Number:
JP14855889A
Publication Date:
February 06, 1990
Filing Date:
June 13, 1989
Export Citation:
Assignee:
HOECHST AG
International Classes:
A61P3/06; A61P9/10; A61K31/575; C07F9/655; C07J9/00; C07J17/00; C07J31/00; C07J53/00; (IPC1-7): A61K31/575; C07J9/00
Attorney, Agent or Firm:
Chika Takagi (2 outside)