COMPOSITION AND METHOD USING ANTI-CSI ANTIBODY FOR TREATING MULTIPLE MYELOMA

Title:

COMPOSITION AND METHOD USING ANTI-CSI ANTIBODY FOR TREATING MULTIPLE MYELOMA

Document Type and Number:

Japanese Patent JP2014040421

Kind Code:

A

Abstract:

To provide a pharmaceutical composition for treatment of multiple myeloma.

A pharmaceutical composition for treatment of multiple myeloma in a subject comprises (a) HuLuc63 which is a humanized IgG1 antibody having a heavy chain variable region corresponding to sequence number 5 and a light chain variable region corresponding to sequence number 6 and (b) dexamethasone, where any other active ingredient is not administered to the subject. And a pharmaceutical composition comprises (a) HuLuc63 which is a humanized IgG1 antibody having a heavy chain variable region corresponding to sequence number 5 and a light chain variable region corresponding to sequence number 6, (b) dexamethasone and (c) thalidomide, where any other active ingredient is not administered to the subject.

Inventors:

AFAR DANIEL

Application Number:

JP2013178996A

Publication Date:

March 06, 2014

Filing Date:

August 30, 2013

Export Citation:

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Assignee:

AVVI BIOTHERAPEUTICS INC

International Classes:

A61K39/395; A61K31/454; A61K31/573; A61K33/243; A61P7/00; A61P35/00; A61P43/00

Domestic Patent References:

JP5340935B2	2013-11-13
JP5340935B2	2013-11-13

Foreign References:

US20060024296A1	2006-02-02
US20060024296A1	2006-02-02

Other References:

JPN6012047163; Ｊ．Ｃｌｉｎ．Ｏｎｃｏｌ．，　２００６．１．２０，　Ｖｏｌ．　２４，　Ｎｏ．　３，　Ｐ．　４３１-４３６
JPN6012047163; Ｊ．Ｃｌｉｎ．Ｏｎｃｏｌ．，　２００６．１．２０，　Ｖｏｌ．　２４，　Ｎｏ．　３，　Ｐ．　４３１-４３６

Attorney, Agent or Firm:

Kawaguchi International Patent Office

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