Title:
薬物耐性結核菌の検出のための組成物及び方法
Document Type and Number:
Japanese Patent JP7036595
Kind Code:
B2
Abstract:
Methods for the rapid detection of the presence or absence of Mycobacterium tuberculosis (MTB) resistant to rifampicin (MTB-RIF) and/or MTB resistant to isoniazid (MTB-INH) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the genes for rpoB, inhA, and katG, along with kits are provided that are designed for the detection of MTB-RIF and/or MTB-INH.
Inventors:
Jenny A. Johnson
Rochaku Mefta
Andy Yuen
Rochaku Mefta
Andy Yuen
Application Number:
JP2017531848A
Publication Date:
March 15, 2022
Filing Date:
December 18, 2015
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C12Q1/689; C12N15/09; G01N33/53; G01N33/533; G01N33/569
Domestic Patent References:
| JP2013502922A | ||||
| JP2012518422A |
Foreign References:
| US20100261163 | ||||
| CN1408882A | ||||
| CN1311435A | ||||
| WO2011140237A2 | ||||
| WO2013009084A2 |
Other References:
J Clin Microbiol, 2008, Vol.46, No.2, pp.689-699
Braz J Infect Dis, 2012, Vol.16, No.1, p.57-62
PloS One, 2012, Vol.7, Issue 5, e37956, p.1-5
Braz J Infect Dis, 2012, Vol.16, No.1, p.57-62
PloS One, 2012, Vol.7, Issue 5, e37956, p.1-5
Attorney, Agent or Firm:
Aoki Atsushi
Ishida Kei
Fukumoto product
Tetsuji Koga
Youichi Watanabe
Ryotaro Takei
Takahide Sasaki
Ishida Kei
Fukumoto product
Tetsuji Koga
Youichi Watanabe
Ryotaro Takei
Takahide Sasaki