脱髄疾患および麻痺のための組成物ならびに再有髄化剤を投与することによるそれらの治療

Title:

脱髄疾患および麻痺のための組成物ならびに再有髄化剤を投与することによるそれらの治療

Document Type and Number:

Japanese Patent JP2006516624

Kind Code:

A

Abstract:

The application provides for methods and compositions for inhibiting demyelination, promoting remyelination and/or treating paralysis in a subject in need thereof. Preferably, such compositions include immunoglobulins (e.g., antibodies, antibody fragments, and recombinantly produced antibodies or fragments), polypeptides (e.g., soluble forms of the ligand proteins for integrins) and small molecules, which when administered in an effective amount inhibits demyelination and/or promotes remyelination in a patient. The compositions and methods described herein can also utilize other anti-inflammatory agents used to palliate conditions and diseases associated with demyelination.

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Inventors:

Karlik, Steve, Jay.
Place, Michael, A.
Conrad, Andrey, W.
Grant, Francin, Es.
Semco, Christopher, M.
Dressen, Darren
Messersmith, Elizabeth
Friedman, Stephen
Yednock, Ted

Application Number:

JP2006502997A

Publication Date:

July 06, 2006

Filing Date:

January 26, 2004

Export Citation:

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Assignee:

Elan Pharmaceuticals, Inc.

International Classes:

A61K38/00; A61K6/00; A61K31/10; A61K31/136; A61K31/16; A61K31/185; A61K31/195; A61K31/198; A61K31/21; A61K31/216; A61K31/381; A61K31/395; A61K31/397; A61K31/40; A61K31/415; A61K31/4164; A61K31/427; A61K31/44; A61K31/445; A61K31/47; A61K31/472; A61K31/495; A61K31/496; A61K31/505; A61K31/506; A61K31/5375; A61K31/54; A61K31/541; A61K31/56; A61K31/573; A61K31/60; A61K31/603; A61K31/616; A61K31/618; A61K31/635; A61K38/21; A61K39/395; A61K45/00; A61K45/06; A61P3/00; A61P25/00; A61P29/00; A61P37/06; A61P43/00; A61K

Domestic Patent References:

JP2001512114A	2001-08-21
JP2001512134A	2001-08-21
JP2001512139A	2001-08-21
JP2002512625A	2002-04-23
JP2001517245A	2001-10-02

Attorney, Agent or Firm:

Yasunori Otsuka
Shiro Takayanagi
Yasuhiro Otsuka
Shuji Kimura
Osamu Shimoyama

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