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Title:
瘢痕化抑制と線維症治療を目的とする組成物と方法
Document Type and Number:
Japanese Patent JP5835699
Kind Code:
B2
Abstract:
Methods of treating, reducing or preventing fibrosis or scarring including administering a therapeutic molecular agent selected from the group consisting of an agent that inhibits chaperonin containing Tcomplex polypeptide subunit eta polypeptide ("CCT-eta"), an agent that inhibits a-Smooth Muscle Actin ("a-SMA"), or a combination thereof, are presented. The fibrosis may include Dupuytren's contracture, Peyronie's disease, pulmonary fibrosis, cirrhosis, interstitial lung disease or scarring alopecia.

Inventors:
Cassue Sandeep
Satish rata
Application Number:
JP2013508253A
Publication Date:
December 24, 2015
Filing Date:
April 28, 2011
Export Citation:
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Assignee:
Cassue Sandeep
International Classes:
A61K48/00; A61K31/7105; A61K31/711; A61K31/713; A61K35/76; A61P17/02; A61P43/00
Domestic Patent References:
JP2005529625A
Foreign References:
US20080019941
Other References:
Meilander NJ, et al.,J Control Release,2003年,vol.88, no.2,p.321-31
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Takamitsu Hoshino