電位依存性ナトリウムチャンネル阻害剤として有用である組成物

Japanese Patent JP5438504

B2

The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

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Joshi, Pramod
Klenitzky, Paul
Gonzales, Jesus
One, chian
Wilson, Dean
Termin, Andreas

JP2009505429A

March 12, 2014

April 11, 2007

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VERTEX PHARMACEUTICALS INCORPORATED

C07C311/39; A61K31/18; A61K31/36; A61K31/402; A61K31/41; A61K31/415; A61K31/4164; A61K31/4174; A61K31/433; A61K31/44; A61K31/4406; A61K31/4453; A61K31/4468; A61K31/495; A61K31/505; A61K31/5375; A61P1/04; A61P9/00; A61P9/06; A61P9/10; A61P9/12; A61P13/02; A61P19/02; A61P21/02; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P43/00; C07C317/44; C07D207/327; C07D211/22; C07D211/58; C07D213/56; C07D213/65; C07D213/74; C07D213/82; C07D231/12; C07D233/36; C07D233/64; C07D257/04; C07D265/30; C07D285/08; C07D295/20; C07D317/68

WO2005013914A1

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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