To solve such a problem wherein a conventional peptide is decomposed by human digestive enzyme and weak in proliferation-promoting activity of fibroblast; and to provide a peptide which promotes the proliferation of cells, protects the skin from injury, and can be utilized through mixing it in various foods, drinks, medicines, and cosmetics.
A dipeptide formed by bonding proline or hydroxyproline being an imino acid having an imino group -NH, or a peptide containing such dipeptide, e.g. Pro-Hyp or Pro-Hyp-Gly, has a proliferation-promoting activity of cultured cells and has an injury-healing activity at the time of skin injury. A reagent for cell culture containing a substance bonded between imino acid and imino acid or containing a peptide having a substance bonded between imino acid and imino acid has a proliferation-promoting function of cells, such as fibroblast.
NAKAMURA TAKASHI
IWAI KOJI
TAGUCHI YASUKI
HASEGAWA TAKANORI
MORIMATSU FUMITAKE
TOYOMURA KOJI