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Title:
CRYSTALLINE AND CRYSTALLIZING OR CRYSTALLIZED ROSARTAN ACID ADDUCT AND METHOD OF PURIFICATION OF ROSARTAN
Document Type and Number:
Japanese Patent JP2001226372
Kind Code:
A
Abstract:

To provide crystalline or crystallized acid adducts of rosartan that is useful for obtaining high-purity rosartan and a method for purifying rosartan using the same.

The objective crystalline or crystallized acid adduct of 2-n- butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl) [1,1'-biphenyl]4-yl]methyl]-imidazol-5- methanol is represented by general formula (I) (wherein A means an acid).


Inventors:
KATSURA TADASHI
SHIRATANI HIROSHI
ITAYA NOBUSHIGE
Application Number:
JP2000282853A
Publication Date:
August 21, 2001
Filing Date:
September 19, 2000
Export Citation:
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Assignee:
SUMIKA FINE CHEMICALS CO LTD
International Classes:
A61K31/4178; A61P43/00; C07D403/10; (IPC1-7): C07D403/10
Domestic Patent References:
JPS6323868A1988-02-01
Attorney, Agent or Firm:
Takashima Hajime