Title:
糖尿病の試験
Document Type and Number:
Japanese Patent JP2009545303
Kind Code:
A
Abstract:
A method for diagnosing susceptibility to diabetes in a dog, the method comprising: (a) (i) detecting in a sample from the dog the presence or absence of a genotype in any one of the following immune system genes: CTLA-4, IGF-2, IL-1alpha, IL-4, IL-6, IL-1O, IL-12beta, IFNgamma, PTPN3, PTPN15, PTPN22, TNF, or RANTES; and/or (ii) determining in a sample from the dog whether a genotype identified in Table 1 or 3A, or a genotype in linkage disequilibrium with said genotype identified in Table 1 or 3 A, is present in an insulin or IGF gene of the dog; and/or (iii) determining in a sample from the dog whether a genotype identified in Table 2 or 3B, or a genotype in linkage disequilibrium with said genotype identified in Table 2 or 3B, is absent in an insulin or IGF gene of the dog; and (b) thereby diagnosing whether the dog is susceptible to diabetes.
Inventors:
Fretwell, Neil
Jones, Christopher, Andrew
Short, Andrea, Dawn
Oriel, William, Ernest, Royce
Kennedy, Lorna, Jane
Jones, Christopher, Andrew
Short, Andrea, Dawn
Oriel, William, Ernest, Royce
Kennedy, Lorna, Jane
Application Number:
JP2009522334A
Publication Date:
December 24, 2009
Filing Date:
August 01, 2007
Export Citation:
Assignee:
MARS INCORPORATED
International Classes:
C12N15/09; A23K1/16; A23K1/18; A61K38/28; A61K45/00; A61P3/10; C12Q1/68
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Yasuhito Suzuki