Title:
高分子ミセル及びそれを有効成分として含有する固形がんの診断又は治療剤
Document Type and Number:
Japanese Patent JP5320569
Kind Code:
B2
Abstract:
To provide a new polymer micelle capable of coordinating a metal ion useful as a contrasting agent or a treating agent and having high stability in blood compared with conventional polymer micelles.
The polymer micelle is formed by self aggregation of a block copolymer containing a hydrophilic polymer chain segment and a segment having a plurality of side chains containing a chelating agent, wherein chelating agent residues having a tertiary amino group and a carboxy group are bonded directly or through a linker structure to at least 60% of the multiple side chains.
COPYRIGHT: (C)2010,JPO&INPIT
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Inventors:
Yokoyama Masayuki
Shiraishi Koichi
Yoshie Yoneya
Kumi Kawano
Shiraishi Koichi
Yoshie Yoneya
Kumi Kawano
Application Number:
JP2008169694A
Publication Date:
October 23, 2013
Filing Date:
June 28, 2008
Export Citation:
Assignee:
Kanagawa Academy of Science and Technology
International Classes:
A61K49/00; A61K33/24; A61K47/34; A61K47/48; A61P35/00; C08G81/00
Domestic Patent References:
| JP4892378B2 | ||||
| JP9507876A | ||||
| JP2006188683A |
Foreign References:
| WO2006003731A1 |
Other References:
白石貢一 他,PEG-PLLからなるMRI造影剤の高分子ミセル形成 ,Drug Deliv Syst,2007年,Vol.22, No.3,p.335
白石貢一 他,PEG-PLLを骨格とした高分子ミセルの作製とT1緩和時間 ,日本化学会講演予稿集,2007年,87th, No.1,p.269
財団法人神奈川科学アカデミー 平成18年度研究概要,2007年,p.39-42
白石貢一 他,Drug Deliv Syst,2008年 1月,Vol.23, No.1,p.33-39
白石貢一 他,PEG-PLLを骨格とした高分子ミセルの作製とT1緩和時間 ,日本化学会講演予稿集,2007年,87th, No.1,p.269
財団法人神奈川科学アカデミー 平成18年度研究概要,2007年,p.39-42
白石貢一 他,Drug Deliv Syst,2008年 1月,Vol.23, No.1,p.33-39
Attorney, Agent or Firm:
Patent Service Corporation Tanigawa International Patent Office
Eijiro Tanikawa
Eijiro Tanikawa