Title:
mRNA前駆体のスプライシングを修飾するENA核酸医薬
Document Type and Number:
Japanese Patent JP4777777
Kind Code:
B2
Abstract:
Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.
Inventors:
Masafumi Matsuo
Yasuhiro Takeshima
Makoto Koizumi
Yasuhiro Takeshima
Makoto Koizumi
Application Number:
JP2005510284A
Publication Date:
September 21, 2011
Filing Date:
November 21, 2003
Export Citation:
Assignee:
Masafumi Matsuo
Yasuhiro Takeshima
NPO Duchenne Muscular Dystrophy Research and Treatment Development Support Organization
Kobe Natural Products Chemical Co., Ltd.
Yasuhiro Takeshima
NPO Duchenne Muscular Dystrophy Research and Treatment Development Support Organization
Kobe Natural Products Chemical Co., Ltd.
International Classes:
C12N15/113; A61K31/7105; A61K31/712; A61K31/7125; A61K48/00; A61P21/00; A61P21/04; C07H21/02; C07H21/04; A61K38/00
Domestic Patent References:
| JP2002325582A | 2002-11-12 | |||
| JP2002010790A | 2002-01-15 | |||
| JP2000325085A | 2000-11-28 | |||
| JP2000297097A | 2000-10-24 |
Foreign References:
| WO2002024906A1 | 2002-03-28 |
Attorney, Agent or Firm:
Setuko Mayama
Kenichi Nomura
Kenichi Nomura