Title:
エロンガーゼ遺伝子とその使用
Document Type and Number:
Japanese Patent JP4434944
Kind Code:
B2
Abstract:
The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated fatty acids (i.e., “elongases”) and to uses thereof. At least two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogamma linolenic acid (DGLA) and in the conversion of AA to adrenic acid (ADA), or eicosapentaenoic acid (EPA) to ω3-docosapentaenoic acid (DPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachidonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, ω6-docosapentaenoic acid or ω3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
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Inventors:
Squelge, Pradeep
Leonardo, Amanda Yee
Hwang, Yun-Syon
Pereira, Syuset El
Leonardo, Amanda Yee
Hwang, Yun-Syon
Pereira, Syuset El
Application Number:
JP2004510380A
Publication Date:
March 17, 2010
Filing Date:
May 29, 2003
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
A01H5/00; C12N15/09; A01H1/00; A23D9/00; A23K1/16; A61K8/30; A61K8/36; A61K8/60; A61K8/64; A61K31/202; A61P3/02; A61P3/04; A61P3/10; A61P7/00; A61P7/02; A61P9/10; A61P9/12; A61P11/06; A61P13/04; A61P13/12; A61P15/00; A61P17/00; A61P17/02; A61P17/06; A61P17/16; A61P19/02; A61P19/10; A61P25/00; A61P29/00; A61P31/18; A61Q19/00; C07H21/04; C12N1/12; C12N1/15; C12N1/19; C12N1/20; C12N1/21; C12N5/00; C12N5/10; C12N9/00; C12N9/10; C12N15/00; C12N15/82; C12P7/64; C12P21/06; A61K38/00
Foreign References:
| WO2002008401A1 | ||||
| WO2000012720A1 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura