Title:
ＡＬＡ－ＰＤＴ又はＡＬＡ－ＰＤＤにおける光線力学的効果の増強剤
Document Type and Number:
Japanese Patent JP7026108
Kind Code:
B2
Abstract:
The object of the present invention is to potentiate the photodynamic effect in ALA-PDT and ALA-PDD. The present invention provides a pharmaceutical related to a combination of ALAs and a dynamin inhibitor. [Selected Drawings] None
Inventors:
Masahiro Ishizuka
Takuya Ishii
Nakajima Motoo
Yuya Kitajima
Takuya Ishii
Nakajima Motoo
Yuya Kitajima
Application Number:
JP2019513593A
Publication Date:
February 25, 2022
Filing Date:
April 12, 2018
Export Citation:
Assignee:
SBI Pharma Co., Ltd.
International Classes:
A61K41/00; A61K31/14; A61K31/197; A61P35/00; A61P43/00
Domestic Patent References:
| JP2015536327A |
Foreign References:
| WO2013187069A1 |
Other References:
JOSHI, S. et al.,Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer c,Mol. Cancer, 2011, Vol. 10, No. 78, pp. 1-12
DEFEO-JONES, D. et al.,Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family mem,Mol. Cancer Ther., 2005, Vol. 4, No. 2, pp. 271-279
RODRIGUEZ, L. et al.,Mechanisms of 5-aminolevulic acid ester uptake in mammalian cells,Br. J. Pharmacol., 2006, Vol. 147, pp. 825-833
TRAN, T. T. et al.,Neurotransmitter Transporter Family Including SLC6A6 and SLC6A13 Contributes to the 5-Aminolevulinic,Photochem. Photobiol., 2014, Vol. 90, pp. 1136-1143
Oncology Reports, 2013, Vol.29, pp.911-916
DEFEO-JONES, D. et al.,Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family mem,Mol. Cancer Ther., 2005, Vol. 4, No. 2, pp. 271-279
RODRIGUEZ, L. et al.,Mechanisms of 5-aminolevulic acid ester uptake in mammalian cells,Br. J. Pharmacol., 2006, Vol. 147, pp. 825-833
TRAN, T. T. et al.,Neurotransmitter Transporter Family Including SLC6A6 and SLC6A13 Contributes to the 5-Aminolevulinic,Photochem. Photobiol., 2014, Vol. 90, pp. 1136-1143
Oncology Reports, 2013, Vol.29, pp.911-916
Attorney, Agent or Firm:
Masahiro Nanjo
Ayako Seta
Koichiro Inami
Hidemitsu Hara
Ayako Seta
Koichiro Inami
Hidemitsu Hara