ErbB3-BASED METHOD AND COMPOSITION FOR TREATING NEOPLASM

Japanese Patent JP2010213710

A

To provide a composition and a method for treating neoplasms in mammals, particularly humans.

There are provided a method for preventing, treating or delaying neoplasm in a mammal using an ErbB-3 protein, a nucleic acid encoding the ErbB-3 protein or a functional fragment of the protein; isolated nucleic acids encoding an extracellular domain of the ErbB-3 protein or its functional fragment, substantially purified extracellular domain of the ErbB-3 protein or its functional fragment and antibodies that bind to an epitope in the extracellular domain of the ErbB-3 protein or its functional fragment; and pharmaceutical compositions and/or vaccines comprising the extracellular domain of the ErbB-3 protein or its functional fragment, or encoding nucleic acids and antibodies binding to such extracellular domain or its functional fragments.

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ZHOU MINGDONG

JP2010101148A

September 30, 2010

April 26, 2010

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ZENSUN SHANGHAI SCI TECH LTD

C12N15/09; A61K31/7088; A61K38/00; A61K38/17; A61K39/00; A61K39/395; A61K45/00; A61K48/00; A61P1/04; A61P13/08; A61P15/00; A61P35/00; C07H21/00; C07K14/435; C07K14/47; C07K14/705; C07K14/71; C07K16/28; C07K16/30; C07K16/32; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12P21/02; C12P21/08

JP2000515372A

2000-11-21

JPN6009026093; Ｐｒｏｃ．　Ｎａｔｌ．　Ａｃａｄ．　Ｓｃｉ．　ＵＳＡ． Ｖｏｌ．８６, 1989, ｐ．９１９３-９１９７
JPN6009026092; Ｐｒｏｃ．　Ｎａｔｌ．　Ａｃａｄ．　Ｓｃｉ．　ＵＳＡ． Ｖｏｌ．８７, 1990, ｐ．４９０５-４９０９

Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo

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