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Title:
FOLLICULAR REGULATORY T CELL INCREASING AGENT
Document Type and Number:
Japanese Patent JP2018188436
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide means for increasing follicular regulatory T-cell (Tfr cell) with high safety, for example, Tfr cell increasing agents administered to a subject in which follicular helper T cells (Tfh cell) in blood are excessively increased.SOLUTION: A lactic acid bacterium belonging to Lactobacillus, for example, Lactobacillus paracasei MCC1849 (NITE BP-01633) is contained as an active ingredient in medicines, foods and drinks, food and drink compositions, and feed and the like which are used for increasing Tfr cells.SELECTED DRAWING: None

Inventors:
YAMURA TOSHIYUKI
ITOGA SHOTA
ARAI SATOSHI
IWABUCHI NORISUKE
Application Number:
JP2018089314A
Publication Date:
November 29, 2018
Filing Date:
May 07, 2018
Export Citation:
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Assignee:
UNIV TOKYO
MORINAGA MILK INDUSTRY CO LTD
International Classes:
A61K35/747; A23L33/135; A61P37/02; A61P43/00
Domestic Patent References:
JP2016113378A2016-06-23
Foreign References:
CN104017746A2014-09-03
Other References:
PLOS ONE, 2010, VOL.5 NO.2, ARTICLE.E9009(P.1-11), JPN6022011404, ISSN: 0004736599
炎症と免疫, 2016, VOL.4 NO.6, P.470-476, JPN6022011402, ISSN: 0004736600
日本農芸化学会2016年度大会講演要旨集, 2016, P.4E089, JPN6022011401, ISSN: 0004736601
腸内細菌学雑誌, 2016, VOL.30 NO.2, P.106, JPN6022011399, ISSN: 0004736602
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Shinichi Sanuki
Takeshi Niwa
Masami Isayama
Yu Anzai