Title:
Glycan-specific analysis tool
Document Type and Number:
Japanese Patent JP6360462
Kind Code:
B2
Abstract:
Provided are lectenz molecules, which are mutated carbohydrate processing enzyme enzymes that are catalytically inactive and that have had their substrate affinity increased by at least 1.2 fold. Further provided are methods for making and methods of using such lectenz. Additional mutated proteins following the lectenz approach are further provided.
Inventors:
Woods Robert Jay.
Yan Loretta
Samurai Cowser N.
Yan Loretta
Samurai Cowser N.
Application Number:
JP2015150210A
Publication Date:
July 18, 2018
Filing Date:
July 30, 2015
Export Citation:
Assignee:
University of Georgia Research Foundation, Inc.
Glycosensors and Diagnostics Limited Liability Company
Glycosensors and Diagnostics Limited Liability Company
International Classes:
C12N15/56; A61K38/47; A61P35/00; C12N9/24; C12Q1/34; C40B40/02; G01N33/15; G01N33/50
Domestic Patent References:
| JP2002503093A | ||||
| JP2008518023A | ||||
| JP2008507983A |
Foreign References:
| WO2007130453A1 |
Other References:
THE JOURNAL OF BIOLOGICAL CHEMISTRY,2005年,Vol.280, No.33,pp.29837-29848
THE JOURNAL OF BIOLOGICAL CHEMISTRY,2008年 5月 2日,VOL.283, NO.18,pp.12415-12425
Glycobiology,2008年 4月 4日,vol.18, no.6,pp.426-440
Current Opinion in Chemical Biology,2007年,Vol.11,pp.335-341
THE JOURNAL OF BIOLOGICAL CHEMISTRY,2008年 5月 2日,VOL.283, NO.18,pp.12415-12425
Glycobiology,2008年 4月 4日,vol.18, no.6,pp.426-440
Current Opinion in Chemical Biology,2007年,Vol.11,pp.335-341
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto