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Title:
カリウムチャンネル機能のヘテロ環インヒビター
Document Type and Number:
Japanese Patent JP5209670
Kind Code:
B2
Abstract:
Novel heterocyclo compounds useful as inhibitor of potassium channel function (especially inhibitors of the Kv1 subfamily of voltage gated K+ channels, especially inhibitors Kv1.5 which has been linked to the ultra-rapidly activating delayed rectifier K+ current IKur), their use in the prevention and treatment of IKur-associated disorders, and pharmaceutical compositions containing such compounds.

Inventors:
John Lloyd
Yong Ti Jung
Heather Finley
Lin Yang
Serge Boardone
Michael f gross
Application Number:
JP2010154061A
Publication Date:
June 12, 2013
Filing Date:
July 06, 2010
Export Citation:
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Assignee:
BRISTOL-MYERS SQUIBB COMPANY
ICAGEN, INC.
International Classes:
C07D233/04; C07D401/12; A61K31/445; A61K31/4535; A61K31/454; A61K31/4545; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61K31/55; A61P1/04; A61P3/10; A61P9/00; A61P9/06; A61P11/08; A61P25/06; A61P25/08; A61P25/28; A61P29/00; A61P37/00; A61P43/00; C07D211/26; C07D211/28; C07D211/34; C07D211/58; C07D211/62; C07D211/64; C07D211/96; C07D223/04; C07D401/04; C07D401/06; C07D401/14; C07D403/12; C07D405/04; C07D405/12; C07D409/04; C07D409/12; C07D409/14; C07D413/04; C07D413/06; C07D413/12; C07D413/14; C07D417/06; C07D417/12; C07D521/00
Domestic Patent References:
JP9124600A
Foreign References:
WO2000025786A1
WO2000003743A1
WO2003039440A1
WO2003033486A1
WO2000074769A1
Other References:
STEVENSON,G.I. et al.,J. Med. Chem.,1998年,Vol.41, No.23,p.4623-4635
Chemical Abstracts,1973年,抄録番号81:130784,RN 52661-92-4 1-piperidinecarboxylic acid, 4-(2-furanylmethyl)-4-(3-hydroxyphenyl)-, methyl ester, 5
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka